CD14/SR-A double knock-outs
Availability: in stock, currently can be shipped
To inquire about obtaining these mice contact Mason Freeman.
The CD14 deficient mice used in this intercross were first described in
the publication Moore, KJ,, Andersson LP, Ingalls RR, Monks BG, Li R, Arnaout
MA, Golenbock DT, and MW Freeman. Divergent response to LPS and bacteria
in CD14 deficient murine macrophages. J Immunol 2000;165:4272-4280. The
SR-A null mice were originally generated by Suzuki et al (A role for macrophage
scavenger receptors in atherosclerosis and susceptibility to infection,
Nature; 1997:386:292-296). They were generously provided to the Freeman
lab by Dr. T. Kodama. They have been back-bred in C57BL6/J mice for at least
6 generations. The two strains were intercrossed. These mice are housed
at Charles River Laboratories and will be shipped directly from CRL.
Shipping and handling charges are subject to CRL costs and are borne by
the requesting lab.
Back to Animal models