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CD14/SR-A double knock-outs

Availability: in stock, currently can be shipped

To inquire about obtaining these mice contact Mason Freeman.

The CD14 deficient mice used in this intercross were first described in the publication Moore, KJ,, Andersson LP, Ingalls RR, Monks BG, Li R, Arnaout MA, Golenbock DT, and MW Freeman. Divergent response to LPS and bacteria in CD14 deficient murine macrophages. J Immunol 2000;165:4272-4280. The SR-A null mice were originally generated by Suzuki et al (A role for macrophage scavenger receptors in atherosclerosis and susceptibility to infection, Nature; 1997:386:292-296). They were generously provided to the Freeman lab by Dr. T. Kodama. They have been back-bred in C57BL6/J mice for at least 6 generations. The two strains were intercrossed. These mice are housed at Charles River Laboratories and will be shipped directly from CRL.

Shipping and handling charges are subject to CRL costs and are borne by the requesting lab.

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